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Related Experiment Video

Updated: Jul 1, 2025

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
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SUPRACHOROIDAL SPACE INJECTION TECHNIQUE: Expert Panel Guidance.

Charles C Wykoff1, Robert L Avery2, Mark R Barakat3,4

  • 1Retinal Consultants of Texas, Houston, Texas.

Retina (Philadelphia, Pa.)
|March 7, 2024
PubMed
Summary

Professional guidelines for suprachoroidal space (SCS) injection were developed. Expert consensus confirms SCS injection is a safe and effective method for retinal and choroidal therapeutics delivery.

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Area of Science:

  • Ophthalmology
  • Retinal Therapeutics
  • Drug Delivery Systems

Background:

  • Suprachoroidal space (SCS) injection is an innovative technique for delivering therapeutics to the retina and choroid.
  • Standardized best practices are needed to optimize safety and efficacy.

Purpose of the Study:

  • To develop professional guidelines for best practices in suprachoroidal space (SCS) injection.
  • To establish consensus on SCS injection techniques for retinal therapeutic delivery.

Main Methods:

  • A panel of expert ophthalmologists reviewed published evidence and clinical experience.
  • A live working group meeting defined consensus points and clinical considerations for SCS injection guidelines.

Main Results:

  • Core consensus guidelines for in-office SCS injection were established.
  • SCS injection was confirmed as a safe and effective method for retinal and choroidal therapeutics.
  • Consensus was reached on rationale, benefits, patient preparation, injection technique, and post-injection management.

Conclusions:

  • Expert panel guidelines aim to standardize SCS injection technique for optimal patient safety and outcomes.
  • The guidelines support physician judgment and clinical setting modifications.
  • Further study may refine specific aspects of the SCS injection procedure.