Influence of different intraoperative fluid management on postoperative outcome after abdominal tumours resection
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View abstract on PubMed
Summary
This summary is machine-generated.Intraoperative multimodal monitoring in major abdominal surgery did not reduce hospital stay or morbidity. However, it did lead to improved fluid management and a lower postoperative procalcitonin level, indicating a potential impact on immune response.
Area Of Science
- Anesthesiology
- Surgical Oncology
- Critical Care Medicine
Background
- Intraoperative fluid management is critical in major abdominal surgeries like colorectal and pancreatoduodenectomy.
- Optimizing fluid balance aims to reduce postoperative complications and hospital stay.
- Multimodal monitoring may offer enhanced insights into patient status during surgery.
Purpose Of The Study
- To evaluate if intraoperative multimodal monitoring reduces postoperative morbidity and hospitalisation duration.
- To compare outcomes between standard monitoring and advanced multimodal monitoring in high-risk surgical patients.
- To investigate the impact of monitoring strategies on inflammatory markers.
Main Methods
- Prospective study with two parallel groups: control (standard monitoring) and protocol (multimodal monitoring).
- Inclusion of high-risk patients undergoing major abdominal surgery.
- Randomized allocation to either standard monitoring (44 patients) or multimodal monitoring (44 patients).
Main Results
- No significant difference in median hospital stay (9 days) between groups.
- No difference observed in postoperative renal or cardiac impairment.
- Significantly higher procalcitonin levels in the control group (0.75 mcg/L) compared to the protocol group (0.3 mcg/L).
- Protocol group received significantly more intraoperative fluid (median +1300 ml vs +375 ml).
Conclusions
- Intraoperative multimodal monitoring led to significant differences in fluid management and vasopressor use.
- Higher procalcitonin in the control group suggests altered immune response related to fluid status.
- No observed benefit in reducing postoperative morbidity or hospital stay with multimodal monitoring.
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