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Sweat as a source of non-invasive biomarkers for clinical diagnosis: An overview
Zhiliang Zhang1, Zhanhong Li2, Kunchen Wei3
1Department of Plastic and Reconstructive Surgery, Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China; Department of Plastic and Aesthetic Surgery, Ningbo Hangzhou Bay Hospital, Zhejiang, China.
Abstract:
Sweat has excellent potential as one of the sources of non-invasive biomarkers for clinical diagnosis. It is relatively easy to collect and process and may contain different disease-specific markers and drug metabolites, making it ideal for various clinical applications. This article discusses the anatomy of sweat glands and their role in sweat production, as well as the history and development of multiple sweat sample collection and analysis techniques. Another primary focus of this article is the application of sweat detection in clinical disease diagnosis and other life scenarios. Finally, the limitations and prospects of sweat analysis are discussed.
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