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Updated: Jul 1, 2025

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
Published on: November 1, 2011
Rift Valley Fever
J Brian Kimble1, Leela Noronha1, Jessie D Trujillo2
1Foreign Arthropod-Borne Animal Diseases Research Unit, National Bio and Agro-Defense Facility, USDA, ARS, Manhattan, KS, USA.
Abstract:
Rift Valley fever (RVF) is a zoonotic viral disease that affects domestic and wild ruminants such as cattle, sheep, goats, camels, and buffaloes. Rift valley fever virus (RVFV), the causative agent of RVF, can also infect humans. RVFV is an arthropod-borne virus (arbovirus) that is primarily spread through the bites of infected mosquitoes or exposure to infected blood. RVFV was first isolated and characterized in the Rift Valley of Kenya in 1931 and is endemic throughout sub-Saharan Africa, including Comoros and Madagascar, the Arabian Peninsula (Saudi Arabia and Yemen), and Mayotte.
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Patterns of Fever
Types of Fever
Here are the different types of fever:
Intracellular Movement of Viruses and Bacteria
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