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The Value of Plasma Atherogenic Index in Prognosis of Sudden Hearing Loss
Zehra Betül Paksoy1, Fatma Cemre Sazak Kundi1
1Department of Otorhinolaryngology, Ankara City Hospital, Ankara, Turkey.
The Journal of International Advanced Otology
|March 7, 2024
Summary
The plasma atherogenic index may indicate a poor prognosis for sudden hearing loss. Higher atherogenic index values correlated with poorer hearing recovery outcomes in patients.
Area of Science:
- Cardiology
- Otolaryngology
- Biochemistry
Background:
- Lipid parameters are known to impact hearing loss.
- The prognostic value of the plasma atherogenic index (PAI) in sudden hearing loss (SHL) has not been previously investigated.
- This study explores the relationship between PAI and SHL prognosis.
Purpose of the Study:
- To evaluate the association between plasma atherogenic index and the prognosis of sudden hearing loss.
- To determine if PAI can serve as a predictive marker for SHL treatment outcomes.
Main Methods:
- Plasma atherogenic index was calculated using the log ratio of triglycerides to HDL cholesterol.
- 84 SHL patients were stratified into tertiles based on PAI levels.
- Linear regression analysis assessed the statistical significance of PAI on hearing recovery, measured by audiometer value differences.
Main Results:
- An inverse relationship was observed between PAI and hearing recovery.
- Statistically significant associations (P<0.05) were found between PAI tertiles and hearing improvement at 1000 Hz, 2000 Hz, and 4000 Hz.
- Linear regression indicated PAI as a potential negative prognostic factor for SHL.
Conclusions:
- The plasma atherogenic index may indicate a poor prognosis in patients with sudden hearing loss.
- This is the first study to suggest PAI as a prognostic indicator for SHL.
- Further research is warranted to confirm these findings and explore therapeutic implications.
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