Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Signaling01:30

Bacterial Signaling

32.1K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
32.1K
Transcription01:10

Transcription

147.0K
Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
147.0K
Gene-Environment Interactions01:20

Gene-Environment Interactions

315
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
315

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A nutrient bottleneck controls antibiotic efficacy in structured bacterial populations.

Nature communications·2026
Same author

Morphodynamics of surface-attached active drops.

Nature communications·2026
Same author

<i>Death & Chemotaxis</i>: Bacterial chemotaxis enables collective escape from phage predation.

bioRxiv : the preprint server for biology·2026
Same author

Editorial: Fourth Annual APS DSOFT Gallery of Soft Matter.

Physical review. E·2026
Same author

<i>Naegleria</i> amoebae seek confinement and crawl persistently through narrow spaces.

bioRxiv : the preprint server for biology·2025
Same author

Spatial self-organization of confined bacterial suspensions.

Proceedings of the National Academy of Sciences of the United States of America·2025

Related Experiment Video

Updated: Jul 1, 2025

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains
06:45

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains

Published on: January 18, 2014

8.6K

Interplay between environmental yielding and dynamic forcing modulates bacterial growth.

Anna M Hancock1, Sujit S Datta1

  • 1Chemical and Biological Engineering, Princeton University, Princeton, New Jersey.

Biophysical Journal
|March 8, 2024
PubMed
Summary

Bacterial growth depends on environmental stress. When external stress exceeds the environment's yield stress, nutrient transport improves, supporting growth. Otherwise, limited nutrients arrest microbial proliferation.

More Related Videos

Precise, High-throughput Analysis of Bacterial Growth
09:00

Precise, High-throughput Analysis of Bacterial Growth

Published on: September 19, 2017

24.0K
Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

6.1K

Related Experiment Videos

Last Updated: Jul 1, 2025

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains
06:45

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains

Published on: January 18, 2014

8.6K
Precise, High-throughput Analysis of Bacterial Growth
09:00

Precise, High-throughput Analysis of Bacterial Growth

Published on: September 19, 2017

24.0K
Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

6.1K

Area of Science:

  • Microbiology
  • Biophysics
  • Rheology

Background:

  • Bacterial habitats like biofilms and tissues are rheologically complex with uneven nutrient distribution.
  • External forces dynamically impact these environments, influencing microbial life.

Purpose of the Study:

  • To investigate how rheological properties, external forcing, and nutrient distribution jointly affect bacterial growth.
  • To understand the role of environmental stress in microbial proliferation.

Main Methods:

  • Studied Escherichia coli growth in granular hydrogels with tunable rheological properties.
  • Applied varying levels of external mechanical shaking (forcing).
  • Compared growth under aerobic and anaerobic conditions.

Main Results:

  • Bacterial growth is modulated by the balance between environmental yield stress (σy) and external stress (σ).
  • When external stress exceeds yield stress (σy < σ), environments fluidize, enhancing nutrient transport and supporting growth.
  • When yield stress exceeds external stress (σy > σ), environmental elasticity limits mixing, restricting nutrients and arresting growth.

Conclusions:

  • Revealed a novel mechanism where environmental rheology, not just local forcing, impacts microbial physiology.
  • Environmental stress balance is a key factor in regulating bacterial growth in diverse settings.
  • Findings have implications for understanding microbial life in natural and industrial environments.