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Updated: Jul 1, 2025

The Use of Chemostats in Microbial Systems Biology
Published on: October 14, 2013
A stability analysis of a time-varying chemostat with pointwise delay
Frédéric Mazenc1, Gonzalo Robledo2, Daniel Sepúlveda3
1EPI DISCO Inria-Saclay, Laboratoire des Signaux et Systèmes (UMR CNRS 8506), CNRS, CentraleSupélec, Université Paris-Sud, 3 rue Joliot Curie, 91192, Gif-sur-Yvette, France.
Abstract:
This paper revisits a recently introduced chemostat model of one-species with a periodic input of a single nutrient which is described by a system of delay differential equations. Previous results provided sufficient conditions ensuring the existence and uniqueness of a periodic solution for arbitrarily small delays. This paper partially extends these results by proving-with the construction of Lyapunov-like functions-that the evoked periodic solution is globally asymptotically stable when considering Monod uptake functions and a particular family of nutrient inputs.
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