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Updated: Jul 1, 2025

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Neuromodulation: What the neurointerventionalist needs to know.

Kobina G Mensah-Brown1, Ryan M Naylor1, Stephen Graepel1

  • 1Department of Neurosurgery, Mayo Clinic, Rochester, MN, USA.

Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
|March 8, 2024
PubMed
Summary

This review explores neuromodulation, a technique altering neural activity across nervous systems. It covers technologies, neurological disorders, and the field's history for neuro-adjacent specialists.

Keywords:
Neuromodulationmovementpainstentrode

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Area of Science:

  • Neurology
  • Neuroscience
  • Biomedical Engineering

Background:

  • Neuromodulation involves altering neural activity in the central, peripheral, and autonomic nervous systems.
  • This technique impacts various organ systems, including cardiac, nervous, and gastrointestinal systems.

Purpose of the Study:

  • To provide a foundational understanding of neuromodulation.
  • To review technological systems and neurological disorders targeted by neuromodulation.
  • To offer a historical perspective on the development of neuromodulation.

Main Methods:

  • Literature review of neuromodulation technologies and applications.
  • Historical analysis of key discoveries and inventions in the field.
  • Focus on relevance to neuro-adjacent subspecialties, particularly neurointerventionalists.

Main Results:

  • Neuromodulation encompasses diverse technologies for treating a range of neurological conditions.
  • The field has evolved significantly, driven by pivotal discoveries and innovations.
  • Understanding neuromodulation is crucial for neurointerventionalists and related fields.

Conclusions:

  • Neuromodulation is a versatile therapeutic approach with a rich history.
  • This review serves as a primer for specialists interested in neuromodulation's technological and clinical aspects.
  • The historical context highlights the ongoing advancements and future potential of neuromodulation.