Plant-based dietary patterns and risk of esophageal cancer: A prospective cohort study spanning 17 years
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.A healthy plant-based diet significantly lowers esophageal cancer (EC) risk. Conversely, an unhealthful plant-based diet pattern increases EC risk, highlighting the importance of diet quality in cancer prevention.
Area Of Science
- Nutrition Science
- Oncology
- Epidemiology
Background
- Plant-based diets offer numerous health benefits, particularly in cancer prevention.
- Limited research exists on the specific association between plant-based dietary patterns and esophageal cancer (EC) risk.
Purpose Of The Study
- To investigate the prospective association between three distinct plant-based dietary indices and the risk of developing esophageal cancer.
- To determine if adherence to healthful or unhealthful plant-based dietary patterns influences EC risk.
Main Methods
- A cohort of 15,184 participants from high-risk EC areas in China was followed for over 20 years.
- Dietary patterns were assessed using the overall plant-based diet index (PDI), healthful plant-based diet index (hPDI), and unhealthful plant-based diet index (uPDI).
- Cox proportional hazard regression models were used to calculate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for EC risk.
Main Results
- Higher adherence to a healthful plant-based diet index (hPDI) was associated with a significantly reduced risk of EC (HR=0.50; 95% CI, 0.32-0.77).
- Each 10-point increase in hPDI score correlated with a 58% decrease in EC risk (HR=0.42; 95% CI, 0.27-0.66).
- Conversely, a higher unhealthful plant-based diet index (uPDI) was linked to an increased risk of EC (HR=1.80; 95% CI, 1.16-2.82).
Conclusions
- A healthy, high-quality plant-based dietary pattern is associated with a reduced risk of esophageal cancer.
- Dietary choices emphasizing plant-based foods are crucial for EC prevention strategies.
- Further research should focus on the specific components of plant-based diets that confer protective effects against EC.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...