Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Adequate Gross Resection Margin Length Ensuring Pathologically Complete Resection In Gastrectomy For Gastric Cancer: A Systematic Review And Meta-analysis.

Adequate gross resection margin length ensuring pathologically complete resection in gastrectomy for gastric cancer: A systematic review and meta-analysis.

Masaru Hayami1, Manabu Ohashi1, Nozomi Kurihara2

  • 1Department of Gastroenterological Surgery, Gastroenterological Center Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.

Annals of Gastroenterological Surgery
|March 8, 2024

Related Experiment Videos

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
03:32

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Published on: December 27, 2024

700
Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
10:31

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Published on: August 9, 2016

12.8K
Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
05:16

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors

Published on: February 19, 2022

5.9K

View abstract on PubMed

Summary
This summary is machine-generated.

Determining adequate resection margin (RM) length is crucial for gastric cancer (GC) surgery. This review suggests specific RM lengths for different gastrectomy types to ensure negative margins and improve patient survival.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Positive resection margins (RM) after gastrectomy for gastric cancer (GC) are linked to poorer patient survival.
  • The precise RM length needed to prevent positive margins is not definitively established, creating surgical uncertainty.

Purpose of the Study:

  • To systematically review and define the optimal RM lengths required to achieve a pathologically negative RM in various gastrectomy procedures for GC.

Main Methods:

  • A systematic review of studies identified through major databases (PubMed, Cochrane, Web of Science, ClinicalTrials.gov) up to August 2023.
  • Evaluation of positive RM incidence based on RM length and estimation of potential positive RMs from gross versus pathological discrepancies.
  • Study quality was assessed using the Newcastle-Ottawa Scale.
Keywords:
gastrectomygastric cancernegative resection marginpositive resection margin

Related Experiment Videos

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
03:32

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Published on: December 27, 2024

700
Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
10:31

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Published on: August 9, 2016

12.8K
Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
05:16

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors

Published on: February 19, 2022

5.9K

Main Results:

  • Analysis of 13 studies encompassing 8983 patients.
  • A proximal RM of 6 cm was found to guarantee a negative margin in gastrectomy.
  • Specific lengths were identified: 6 cm proximal RM for distal gastrectomy, 2-2.5 cm esophageal RM for total gastrectomy (depending on invasion), and 4 cm distal RM for proximal gastrectomy in early GC.

Conclusions:

  • This systematic review provides evidence-based recommendations for adequate RM lengths in different gastrectomy types for GC.
  • Adherence to these suggested RM lengths can help ensure a pathologically negative margin, potentially improving oncological outcomes.
resection margin length