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Advances in researches on long coronavirus disease in children: a narrative review

Jiaqian Zhang1, Taiji Kuang1, Xinglou Liu1

  • 1Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Translational Pediatrics
|March 8, 2024
PubMed

Insights

Long COVID in children, a significant post-COVID-19 condition, requires more research. This review summarizes current knowledge on pediatric long COVID to aid clinicians and researchers.

Area of Science:

  • Pediatric Infectious Diseases
  • Public Health
  • Clinical Research

Background:

  • Coronavirus disease 2019 (COVID-19) has led to millions of infections globally.
  • Key pediatric sequelae include multi-system inflammatory syndrome and long COVID.
  • Long COVID presents a higher incidence and broader impact in children compared to other conditions.

Purpose of the Study:

  • To consolidate current knowledge on long COVID in children.
  • To assist pediatricians and researchers in understanding and managing pediatric long COVID.
  • To guide future research and clinical treatment strategies.

Main Methods:

  • A comprehensive literature review was conducted.
  • Studies on "long COVID", pediatric, children, adolescent, and post-COVID syndrome were searched in PubMed.
  • Publications after 2019 were included.

Main Results:

  • The review synthesizes current research on the epidemiology, pathogenesis, and clinical features of pediatric long COVID.
  • Analysis of existing data provides insights into diagnostic approaches for COVID-19 in children.
  • Potential therapeutic interventions for long COVID in children are identified.

Conclusions:

  • This review offers a summary of existing research on pediatric long COVID.
  • Findings aim to support clinical diagnosis, treatment, and prevention efforts.
  • Provides a foundation for further molecular-level research into disease mechanisms.
Abstract

Keywords:
Coronavirus disease 2019 (COVID-19)childrenlong COVIDpediatricspost-acute sequelae of COVID-19

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