Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated Near-Infrared Light-Driven Janus Micromotor-Fluorescent Nanodiamond Dynamic Sensing Platform for Active Motion-Enhanced Biodetection.

ACS sensors·2026
Same author

Plasmonic-Enhanced Dual-Channel Nanodiamonds Fluorescence Emission Coupled with Quantum Sensing for Simultaneous Quantification of Multiple Biomarkers.

ACS sensors·2025
Same author

Detection with Active Capture of Breast Cancer Marker MUC1 Using a MXene-Based Electrochemical Actuator.

ACS applied materials & interfaces·2025
Same author

Color-Coded Traffic Signal Method Combined with Nanodiamond Quantum Sensing for Accurate miRNA Detection.

ACS sensors·2024
Same author

Electrochemical-Enhanced Charge State Modulation of Nitrogen-Vacancy Centers for Ultrasensitive Biodetection of MicroRNA-155.

ACS applied materials & interfaces·2024
Same author

AI-Enhanced Visual-Spectral Synergy for Fast and Ultrasensitive Biodetection of Breast Cancer-Related miRNAs.

ACS nano·2024

Related Experiment Video

Updated: Jul 1, 2025

Simple Bulk Readout of Digital Nucleic Acid Quantification Assays
06:55

Simple Bulk Readout of Digital Nucleic Acid Quantification Assays

Published on: September 24, 2015

8.3K

Digital microfluidics methods for nucleic acid detection: A mini review.

Youqiang Xing1, Yan Wang2, Xiang Li3

  • 1School of Mechanical Engineering, Southeast University, Nanjing 211189, Jiangsu Province, People's Republic of China.

Biomicrofluidics
|March 8, 2024
PubMed
Summary

Digital microfluidics offers rapid, high-throughput infectious disease detection. This technology enables portable, low-reagent testing for effective virus containment and public health management.

More Related Videos

Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

22.2K
A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
14:53

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

17.2K

Related Experiment Videos

Last Updated: Jul 1, 2025

Simple Bulk Readout of Digital Nucleic Acid Quantification Assays
06:55

Simple Bulk Readout of Digital Nucleic Acid Quantification Assays

Published on: September 24, 2015

8.3K
Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

22.2K
A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
14:53

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

17.2K

Area of Science:

  • Biotechnology
  • Medical Diagnostics
  • Microfluidics

Background:

  • Infectious diseases pose significant global health challenges.
  • Traditional nucleic acid testing methods are often slow, complex, and require specialized facilities.
  • Limitations in current methods hinder rapid, large-scale detection and isolation of infected individuals.

Purpose of the Study:

  • To explore the potential of digital microfluidics for infectious disease detection.
  • To highlight the advantages of digital microfluidic chips over traditional testing methods.
  • To assess the role of these technologies in public health outbreak management.

Main Methods:

  • Leveraging principles of electrokinetics, acoustics, optics, magnetism, and mechanics.
  • Developing digital microfluidic chips for bioassays.
  • Integrating microfluidic technology into point-of-care testing devices.

Main Results:

  • Digital microfluidic chips provide high detection throughput and functional integration.
  • These chips significantly reduce reagent consumption, leading to cost savings.
  • The portability of digital microfluidic devices enables onsite testing in diverse settings.

Conclusions:

  • Digital microfluidics presents a promising advancement for infectious disease detection and control.
  • Rapid, high-throughput, and portable testing capabilities enhance virus containment strategies.
  • This technology improves the management of public health outbreaks, especially in resource-limited areas.