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Updated: May 2, 2026
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Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
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Iatrogenic myelodysplastic syndrome complicating multiple sclerosis: A case report
Konrad Kubicki1, Dusan Stefoski1
1Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
Multiple Sclerosis (Houndmills, Basingstoke, England)
|March 9, 2024
Summary
This case report details a patient who developed myelodysplastic syndrome (MDS) after treatment with dimethyl fumarate (DMF) for multiple sclerosis. It suggests caution with immunosuppressants due to potential links with DMF and cladribine.
Area of Science:
- Neurology
- Hematology
- Oncology
Background:
- Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
- Disease-modifying therapies (DMTs) for MS include various immunosuppressants.
- Prior treatments in this patient included intravenous (IV) cladribine and natalizumab.
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