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Integrated Compensatory Responses in a Human Model of Hemorrhage
Published on: November 20, 2016
Mortality in hypotensive combat casualties who require emergent laparotomy in the forward deployed environment
Luke Pumiglia1, James M Williams1, Marissa Beiling2
1Madigan Army Medical Center, Department of Surgery, 9040 Jackson Avenue, Joint Base Lewis-McChord, WA, 98431, USA.
Introduction:
Mortality rates among hypotensive civilian patients requiring emergent laparotomy exceed 40%. Damage control (DCR) principles were incorporated into the military's Clinical Practice Guidelines (CPG) in 2008. We examined combat casualties requiring emergent laparotomy to characterize how mortality rates compare to hypotensive civilian trauma patients.
Methods:
The DoD Trauma Registry (2004-2020) was queried for adults who underwent combat laparotomy. Patients who were hypotensive were compared to normotensive patients. Mortality was the outcome of interest. Mortality rates before (2004-2007) and after (2009-2020) DCR CPG implementation were analyzed.
Results:
1051 patients were studied. Overall mortality was 6.5% for normotensive casualties and 28.7% for hypotensive casualties. Mortality decreased in normotensive patients but remained unchanged in hypotensive patients following the implementation of the DCR CPG.
Conclusion:
Hypotensive combat casualties undergoing emergent laparotomy demonstrated a mortality rate of 29.5%. Despite many advances, mortality rates remain high in hypotensive patients requiring emergent laparotomy.

