Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

11.2K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
11.2K
DNA Packaging00:58

DNA Packaging

102.5K
Overview
102.5K
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

46.9K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
46.9K
Next-generation Sequencing03:00

Next-generation Sequencing

88.8K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
88.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiscale dynamics of special memristive ion channels in a neural circuit.

Chaos (Woodbury, N.Y.)·2026
Same author

Predicting protein-protein interaction sites based on dynamic perception mechanism within a hierarchical E(n)-equivariant graph.

Briefings in bioinformatics·2026
Same author

Directly Encrypting DNA Sequences for Secure DNA Storage via Automata Cryptography.

IEEE transactions on nanobioscience·2026
Same author

Baduanjin exercise with or without traditional Chinese tuina therapy for nonspecific chronic neck pain: study protocol for a randomised controlled trial.

Frontiers in sports and active living·2026
Same author

Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning.

Synthetic and systems biotechnology·2026
Same author

Integrating histology and spatial transcriptomics via multimodal transformers and contrastive representation learning for accurate gene expression prediction.

Journal of biomedical informatics·2026

Related Experiment Video

Updated: Jul 1, 2025

Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level
08:56

Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level

Published on: July 17, 2018

7.6K

DNA-QLC: an efficient and reliable image encoding scheme for DNA storage.

Yanfen Zheng1, Ben Cao1, Xiaokang Zhang1

  • 1School of Computer Science and Technology, Dalian University of Technology, Lingshui Street, DalianLiaoning, 116024, China.

BMC Genomics
|March 9, 2024
PubMed
Summary

DNA storage offers high capacity but faces challenges. DNA-QLC enhances image reconstruction by improving coding density and error correction, making DNA storage more reliable for multimedia data.

Keywords:
Combinatorial constraintImage reconstructionLevenshtein codeNet information density

More Related Videos

Simple Bulk Readout of Digital Nucleic Acid Quantification Assays
06:55

Simple Bulk Readout of Digital Nucleic Acid Quantification Assays

Published on: September 24, 2015

8.3K
Quasi-light Storage for Optical Data Packets
07:45

Quasi-light Storage for Optical Data Packets

Published on: February 6, 2014

10.8K

Related Experiment Videos

Last Updated: Jul 1, 2025

Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level
08:56

Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level

Published on: July 17, 2018

7.6K
Simple Bulk Readout of Digital Nucleic Acid Quantification Assays
06:55

Simple Bulk Readout of Digital Nucleic Acid Quantification Assays

Published on: September 24, 2015

8.3K
Quasi-light Storage for Optical Data Packets
07:45

Quasi-light Storage for Optical Data Packets

Published on: February 6, 2014

10.8K

Area of Science:

  • Bioinformatics
  • Data Storage Technologies
  • Information Theory

Background:

  • DNA storage presents significant advantages in capacity, stability, and energy efficiency for multimedia data.
  • Current limitations include low coding density and insufficient error correction capabilities.

Purpose of the Study:

  • To enhance the efficiency and reliability of DNA-based image storage and reconstruction.
  • To address the limitations of low coding density and weak error correction in DNA data storage.

Main Methods:

  • Development of DNA-QLC, integrating a quantized ResNet Variational Autoencoder (QRes-VAE) for image compression.
  • Utilization of Levenshtein coding (LC) for robust DNA sequence error correction.

Main Results:

  • DNA-QLC achieves a net information density 2.4 times greater than DNA Fountain.
  • Demonstrated high-fidelity image reconstruction (SSIM of 0.917) even at a 2% error rate.
  • Generated DNA sequences adhere to combinatorial constraints.

Conclusions:

  • The DNA-QLC encoding scheme significantly improves the efficiency and reliability of DNA storage systems.
  • Enhanced performance boosts the potential of DNA storage for storing multimedia information, particularly images.