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Related Concept Videos

Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Alzheimer's Disease: Treatment01:22

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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Amnesia01:13

Amnesia

126
Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
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Freudian Psychology01:26

Freudian Psychology

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Sigmund Freud, an Austrian neurologist born in 1856, significantly influenced psychology through his exploration of the unconscious mind. His interest in patients suffering from hysteria and neurosis — conditions without apparent physical causes — led him to theorize the existence of an unconscious mind, a repository for feelings and urges beyond our awareness. Freud's innovative approach included techniques such as dream analysis, free association, and attention to slips of the...
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Updated: Jul 1, 2025

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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Digging Deeper: What Can We Really Learn about Dementia from History?

Jesse Ballenger1, Daniel R George2, Peter J Whitehouse3,4

  • 1Drexel University College of Nursing and Health Professions, Philadelphia, PA, USA.

Journal of Alzheimer'S Disease : JAD
|March 10, 2024
PubMed
Summary

This study argues against environmental toxins causing advanced dementia, advocating for historical context in ancient texts. It also notes declining dementia rates in Western nations due to public health factors influencing brain health.

Keywords:
Alzheimer’s diseasedementiaenvironmental factorshistorypublic health

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Area of Science:

  • Neuroscience
  • History
  • Public Health

Background:

  • Finch and Burstein propose environmental toxins and lifestyle factors in post-industrial societies cause advanced dementias.
  • This perspective challenges traditional understandings of dementia etiology.

Purpose of the Study:

  • To advocate for a more rigorous historical approach to understanding dementia.
  • To emphasize contextualizing ancient texts within their historical and cultural settings.
  • To explore population-level factors influencing dementia rates.

Main Methods:

  • Historical text analysis
  • Review of epidemiological data on dementia rates
  • Analysis of public health policies and social determinants of brain health

Main Results:

  • Declining relative dementia rates observed in Western countries.
  • Identified population health factors and policies linked to reduced dementia risk.
  • Highlighted the influence of social determinants on brain health.

Conclusions:

  • A rigorous historical and contextual approach is crucial for dementia research.
  • Public health initiatives and social determinants significantly impact dementia risk.
  • Environmental toxin theories require further contextualization within broader societal factors.