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TLRs1-10 Protein Expression in Circulating Human White Blood Cells during Bacterial and COVID-19 Infections

Louise Chomel1, Mathieu Vogt2, Julien Demiselle3,4

  • 1INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM), CRBS (Centre de Recherche en Biomédecine de Strasbourg), FMTS (Fédération de Médecine Translationnelle de Strasbourg), University of Strasbourg, Strasbourg, France, louise.chomel@etu.unistra.fr.

Journal of Innate Immunity
|March 10, 2024
PubMed
Summary

Toll-like receptor (TLR) expression differs in sepsis and COVID-19. Septic shock shows reduced TLR4, while severe COVID-19 and septic shock increase TLR7, highlighting distinct immune responses in critical infections.

Keywords:
COVID-19MonocytesNeutrophilsSeptic shockToll-like receptors

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