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Updated: Jul 1, 2025

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Hybrid Interventions in Congenital Heart Disease: A Review of Current Practice and Rationale for Use
Jeffrey D Zampi1, C Todd Sower1, Timothy S Lancaster2
1Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan.
Background:
Hybrid interventions have become a common option in the management for a variety of patients with congenital heart disease. In this review, we discuss the data that have driven decision making about hybrid interventions to date.
Methods:
The existing literature on various hybrid approaches was reviewed and summarized. In addition, the key tenants to creating a successful hybrid program within a congenital heart center are elucidated.
Results:
Hybrid strategies for single-ventricle patients, pulmonary atresia with intact ventricular septum, branch pulmonary artery stenosis, and muscular ventricular septal defect closure have important benefits and limitations compared with traditional approaches.
Conclusion:
A growing body of evidence supports the use of hybrid interventions in congenital heart disease. But important questions remain regarding improved survival and other long-term outcomes, such as neurocognition, that might impact widespread adoption as a primary treatment strategy.

