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Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
Correlation between maternal and infant vitamin B12 levels in severe malnutrition in infants under 6 months
Arushi Singhal1, Anurag Singh1, Damini Sharma1
1Department of Paediatrics, Dr SN Medical College and Hospital, Jodhpur, India.
Insights
Maternal and infant serum vitamin B12 levels are positively correlated in malnourished infants aged 1-6 months. This highlights the need for targeted nutrition interventions for mothers and babies to improve health outcomes.
Area of Science:
- Nutritional Science
- Pediatric Health
- Maternal Health
Background:
- Malnutrition is a global health concern, especially for infants under six months.
- Vitamin B12 is crucial for infant neurological development and overall maternal-infant health.
Purpose of the Study:
- To investigate the correlation between maternal and infant serum vitamin B12 levels in severely malnourished infants (1-6 months).
- To assess this correlation in tertiary care hospitals in western Rajasthan.
Main Methods:
- A cross-sectional study involving 110 mother-infant pairs.
- Participants were recruited from a Nutrition Rehabilitation Center in Rajasthan, India.
- Simple random sampling was employed after ethical approval.
Main Results:
- Severe malnutrition was most prevalent in infants aged 1-2 months.
- A significant positive correlation was observed between maternal and infant serum vitamin B12 levels (p < 0.001).
- Exclusive breastfeeding showed a positive correlation with age-appropriate milestones (p = 0.033).
Conclusions:
- The study underscores the critical link between maternal and infant vitamin B12 status.
- Targeted nutritional interventions focusing on vitamin B12 are essential for maternal and infant well-being.
Background:
Malnutrition poses a significant global health challenge, affecting various age groups, with infants under 6 months being particularly vulnerable. Vitamin B12, an essential micronutrient critical for neurological development, has been identified as a key player in the overall health of both mothers and infants.
Aim:
To find the correlation between serum vitamin B12 levels in infants, 1-6 months of age with severe malnutrition and maternal levels at tertiary care hospitals in western Rajasthan.
Methods:
The cross-sectional study was conducted in the UNICEF Regional Center of Excellence-supported Nutrition Rehabilitation Center in Rajasthan, India, through simple random sampling. One hundred ten infants with their mothers were enrolled after consent and approval from the Institutional Ethics Committee.
Results:
Severe malnutrition predominantly affected infants aged 1-2 months, with 77% born small for gestational age and 66.4% belonging to the multiple birth order group. Serum vitamin B12 levels showed a significant positive correlation between mothers and infants (p < 0.001), while exclusive breastfeeding correlated positively with age-appropriate milestones (p = 0.033).
Conclusion:
The findings emphasize the importance of targeted interventions addressing maternal and infant nutrition, with a focus on ensuring adequate vitamin B12 levels.
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