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Predictive value of background parenchymal enhancement on breast magnetic resonance imaging for pathological tumor
1Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.
Summary
Background parenchymal enhancement (BPE) on breast MRI shows potential as an imaging biomarker for predicting pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT). Further large-scale studies are needed to confirm this association.
Area of Science:
- Oncology
- Radiology
- Biomarkers
Background:
- Background parenchymal enhancement (BPE) on breast MRI is a potential imaging biomarker.
- Predicting pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT) is crucial for breast cancer treatment.
- Assessing BPE's predictive value for pCR is an active area of research.
Conclusions:
- Changes in BPE may serve as a promising imaging biomarker for predicting pCR in breast cancer.
- Current evidence is limited, especially from quantitative BPE measurements.
- Prospective, multicenter, large-sample studies are required to validate BPE's predictive role.
