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Related Concept Videos

Bacterial Signaling01:30

Bacterial Signaling

32.1K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
32.1K
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  6. Disruption Of Communication: Recent Advances In Antibiofilm Materials With Anti-quorum Sensing Properties.

Disruption of Communication: Recent Advances in Antibiofilm Materials with Anti-Quorum Sensing Properties.

Yangcui Qu1, Yi Zou2, Guannan Wang3

  • 1College of Medical Engineering & the Key Laboratory for Medical Functional Nanomaterials, Jining Medical University, Jining, 272067, P. R. China.

ACS Applied Materials & Interfaces
|March 11, 2024

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Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
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Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
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Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms
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View abstract on PubMed

Summary
This summary is machine-generated.

Preventing bacterial biofilm formation is crucial for public health and industry. This review explores antiquorum sensing materials, including nanomaterials, surfaces, and hydrogels, as innovative strategies to inhibit bacterial communication and prevent biofilms.

Area of Science:

  • Materials Science
  • Microbiology
  • Biotechnology

Background:

  • Biofilm contamination poses significant risks to public health, food safety, and marine environments.
  • Established methods struggle with the complete eradication of mature biofilms due to their persistent nature.
  • Targeting bacterial communication systems like quorum sensing offers a promising alternative for biofilm prevention.

Purpose of the Study:

  • To review recent advancements in materials designed to inhibit biofilm formation by targeting quorum sensing.
  • To categorize and discuss the efficacy of different classes of antiquorum sensing materials.

Main Methods:

  • Literature review of recent research on antiquorum sensing materials.
  • Categorization of materials into antibiofilm nanomaterials, surfaces, and hydrogels.
Keywords:
Antibiofilm materialsHydrogelsNanomaterialsQuorum sensing inhibitors

Related Experiment Videos

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
07:47

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases

Published on: January 1, 2016

11.5K
Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

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Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms
03:29

Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms

Published on: May 31, 2024

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  • Analysis of the mechanisms by which these materials interfere with bacterial quorum sensing.
  • Main Results:

    • Antiquorum sensing materials show potential in preventing biofilm formation.
    • Key material types include nanomaterials, functionalized surfaces, and specialized hydrogels.
    • These materials disrupt bacterial communication, thereby inhibiting biofilm development.

    Conclusions:

    • Materials targeting quorum sensing represent a strategic approach to combat biofilm formation.
    • Further research is needed to address current challenges and explore future applications.
    • Innovative solutions are essential to overcome the limitations of traditional biofilm eradication methods.
    Surfaces