Adult congenital heart diseases: systematic review/meta-analysis

Ahmdelmukashfi M Elmustfa A Azem Mahmod1, Shima Hassan Mohammed Koko2

  • 1Faculty of Medicine and Health Sciences, Red Sea University, Port Sudan.

Insights

Adults with congenital heart disease (CHD) report a lower quality of life (QOL) across all aspects. Factors like age, anxiety, depression, and female gender contribute to diminished QOL in CHD patients.

Area of Science:

  • Cardiology
  • Public Health
  • Quality of Life Research

Background:

  • Congenital heart disease (CHD) represents significant structural heart abnormalities impacting patient function.
  • Assessing the quality of life (QOL) for CHD patients is crucial for researchers and clinicians.
  • A systematic review is needed to consolidate existing knowledge on CHD patient QOL.

Purpose of the Study:

  • To systematically review and assess the quality of life (QOL) in adult patients diagnosed with congenital heart disease (CHD).

Main Methods:

  • Searched PubMed and Google Scholar for studies published between 2020-2022.
  • Utilized keywords: "QOL, Adults, CHD, Outcomes, Impact, Effects, Life of CHD Patients."
  • Included original, full-text English articles focusing on adult CHD patients' QOL.

Main Results:

  • Seven eligible studies were identified from 5455 initial articles.
  • The review encompassed 8445 adult CHD patients and 104 healthy controls.
  • Investigated QOL dimensions included physical/psychological health, mental well-being, anxiety, and depression.

Conclusions:

  • Adults with congenital heart disease consistently report a reduced quality of life.
  • Risk factors for poor QOL in this population include older age, anxiety, depression, and being female.
Abstract

Related Concept Videos

Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
911
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
1.0K
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
1.3K
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
548
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
812
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
762