Related Experiment Video For metastatic gastric adenocarcinoma
Updated: Jul 1, 2025

Detection of a CDH1 Rare Transcript Variant in Fresh-frozen Gastric Cancer Tissues by Chip-based Digital PCR
Published on: February 5, 2018
A Rare Case of Cutaneous Gastric Adenocarcinoma With Signet Ring Cell Features
Alexander Garcia1, Arman Maqsudlu1, Ishita Dhawa2
1Department of Medicine, Cooper University Hospital, Camden, NJ.
Abstract:
Cutaneous metastatic disease from primary gastric cancer is quite scarce, often going unrecognized. In this case, the patient presented with an expanding rash that was biopsied, with findings concerning for metastatic adenocarcinoma from a suspected luminal upper gastrointestinal origin. Subsequent biopsies during an esophagogastroduodenoscopy confirmed poorly differentiated adenocarcinoma with signet ring cell features, most likely from an upper gastrointestinal primary (gastric vs gastroesophageal junction). We review this case to help providers identify signet cell type cutaneous metastases of gastric cancer quickly to improve patient outcomes.
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