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Updated: Jul 22, 2026

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
Cutaneous signs of selected cardiovascular disorders: A narrative review
Marium Asif1, Muhammad Hamza Yousuf1, Usman Shakeel Farooqui1
1Faculty of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Insights
Clinicians should recognize skin findings like rashes and petechiae as potential indicators of cardiovascular diseases. Early identification of these cutaneous signs aids in diagnosis and guides appropriate treatment strategies.
Area of Science:
- Cardiology
- Dermatology
- Internal Medicine
Background:
- Cardiovascular diseases (CVD) are a primary global cause of death and illness.
- Cutaneous manifestations are recognized in some CVDs, but a comprehensive understanding is lacking.
- Prompt diagnosis and management of CVD are crucial.
Purpose of the Study:
- To review key cutaneous signs associated with various cardiovascular diseases.
- To highlight the diagnostic value of skin findings in cardiology.
- To discuss current management strategies for CVD presenting with dermatological symptoms.
Main Methods:
- Literature review of studies on cardiovascular diseases and their cutaneous manifestations.
- Analysis of distinctive skin findings and their correlation with specific cardiovascular conditions.
- Synthesis of information on diagnostic approaches and treatment recommendations.
Main Results:
- Identified specific skin findings (petechiae, macules, purpura, lentigines, rashes) indicative of underlying cardiovascular disease.
- Demonstrated the importance of dermatological signs in diagnosing conditions like infectious endocarditis and acute rheumatic fever.
- Highlighted the need to consider cutaneous signs in a broader range of cardiovascular pathologies.
Conclusions:
- Cutaneous signs serve as valuable diagnostic clues for cardiovascular diseases.
- Integrating dermatological assessment into cardiovascular evaluation can improve diagnostic accuracy.
- Updated management strategies for cardiovascular diseases with skin manifestations are essential for effective patient care.
Abstract:
Cardiovascular diseases are the leading cause of mortality and morbidity globally. Clinicians must know cutaneous signs of cardiovascular disease, including petechiae, macules, purpura, lentigines, and rashes. Although cutaneous manifestations of diseases like infectious endocarditis and acute rheumatic fever are well established, there is an indispensable need to evaluate other important cardiovascular diseases accompanied by cutaneous signs. Moreover, discussing the latest management strategies in this regard is equally imperative. This review discusses distinctive skin findings that help narrow the diagnosis of cardiovascular diseases and recommendations on appropriate treatment.
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