Comparison between myocardial infarction with non-obstructive coronaries (MINOCA) and myocardial infarct patients...

Area of Science:

• Cardiology
• Clinical Research
• Public Health

Background:

• Myocardial infarction (MI) can occur with normal or near-normal coronary arteries, a condition termed MINOCA.
• MINOCA diagnosis presents a clinical challenge, necessitating comparison with MI-CAD.

Purpose of the Study:

• To compare one-year mortality rates between MINOCA and MI-CAD patients.
• To identify risk factors associated with MINOCA and MI-CAD.

Main Methods:

• A retrospective cohort study of 679 STEMI patients undergoing primary PCI from 2018-2019.
• Data on demographics, clinical variables, ECG findings, and one-year mortality were extracted from the MI registry.

Main Results:

• The estimated frequency of MINOCA was 4.6%.
• MINOCA patients were significantly younger (47.14±6.2 vs 57.61±9.1 years) and had higher LVEF (47.4±9.47% vs 43.5±6.8%) compared to MI-CAD patients.
• No significant difference in one-year mortality was observed between MINOCA and MI-CAD groups (P =0.07).

Conclusions:

• The prevalence of MINOCA in Yazd aligns with global figures.
• Despite younger age, better LV function, and fewer CAD risk factors, MINOCA patients do not appear to have a better prognosis than MI-CAD patients.