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Published on: September 5, 2020
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Dynamic Mode Decomposition for Transient Cavitation Bubbles Imaging in Pulsed High Intensity Focused Ultrasound
Minho Song1, Oleg A Sapozhnikov2,3, Vera A Khokhlova2,3
1Department of Mechanical Engineering, University of Washington, Seattle, WA 98195 USA.
Biorxiv : the Preprint Server for Biology
|March 11, 2024
Summary
Dynamic Mode Decomposition enhances Bubble Doppler imaging for mapping cavitation bubbles during pulsed high-intensity focused ultrasound (pHIFU) treatment. This method offers quantitative metrics for monitoring tissue damage progression.
Area of Science:
- Medical Imaging
- Acoustic Physics
- Biomedical Engineering
Background:
- Pulsed high-intensity focused ultrasound (pHIFU) induces cavitation bubbles for tissue disruption without contrast agents.
- Mapping these transient bubbles and quantifying tissue damage is challenging due to bubble size and rapid dissolution.
- Conventional Bubble Doppler imaging is limited by wall filters optimized for blood flow, not transient scatterers.
Conclusions:
- Dynamic Mode Decomposition is an effective enhancement for Bubble Doppler imaging, enabling precise mapping of transient cavitation bubbles.
- This approach provides new quantitative metrics for real-time monitoring of tissue response during pHIFU treatments.
- DMD offers a promising tool for advancing the precision and efficacy of focused ultrasound therapies.
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