Progressive multifocal leukoencephalopathy in a lung transplant recipient

Jason Sakizadeh1, Michael J Davis2, Lauren Fontana2

  • 1University of Minnesota Medical School Twin Cities Campus Minneapolis MN USA.

Clinical Case Reports
|March 11, 2024
PubMed

Insights

Progressive multifocal leukoencephalopathy (PML) is a rare, fatal CNS disease. Early diagnosis of PML within a year after lung transplant is crucial.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Transplant Medicine

Background:

  • Progressive multifocal leukoencephalopathy (PML) is a rare and fatal demyelinating disease affecting the central nervous system (CNS).
  • PML is caused by the JC virus, often reactivating in immunocompromised individuals.
  • Lung transplant recipients are a vulnerable population for opportunistic infections like PML.