Related Experiment Video
Updated: Jul 1, 2025
Experimental Model to Evaluate Resolution of Pneumonia
Published on: February 17, 2023
C-reactive protein in the early diagnosis of pneumonia complicating severe blunt chest trauma
Becem Trabelsi1, Sahar Ghorbel1, Rania Ben Rabeh2
1Department of Anesthesiology and Intensive Care, Taher Maamouri Teaching Hospital of Nabeul, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Introduction:
The early diagnosis of pneumonia following severe blunt chest trauma (SBCT) allows the early prescription of antibiotics and initiation of adequate supportive care.
Aim:
To assess the usefulness of C-reactive protein (CRP) in the early diagnosis of pneumonia complicating SBCT.
Methods:
We conducted a prospective study of patients admitted to trauma intensive care unit for SBCT between January 2020 and February 2023. Patients were divided into two groups according to whether or not they developed pneumonia. The CRP levels were monitored daily.
Results:
One hundred sixty-seven patients were included. Pneumonia occurred in 40.1% of patients within a median of 5 days. We found statistically significant difference in mean CRP levels between groups from day 3 to day 9 following trauma. The increase in CRP level on the 4th day from a value greater than or equal to 192 mg/L was a marker of early diagnosis of pneumonia (sensitivity 80.6%; specificity 80.8%).
Conclusion:
Daily CRP measurement from the 3rd day following SBCT may be useful for early diagnosis of pneumonia complicating SBCT.
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