Related Experiment Video
Updated: Jul 1, 2025

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
Published on: October 20, 2021
Changing Stimulation Frequency Improves Implanted Peripheral Nerve Stimulator Effects After Posttraumatic Total Hip
Chris J Pierson1, Natalie Velez, Nitin B Jain
1From the Department of Applied Clinical Research, The University of Texas Southwestern Medical Center, Dallas, Texas (CJP); The University of Texas Southwestern Medical Center School of Medicine, Dallas, Texas (NV); and Department of Physical Medicine & Rehabilitation, The University of Texas Southwestern Medical Center, Dallas, Texas (NBJ, CK).
Peripheral nerve stimulation effectively managed chronic pain and weakness after total hip arthroplasty. This non-pharmacological approach improved patient function and strength, offering a new treatment avenue.
Area of Science:
- Orthopedic Surgery
- Pain Management
- Neuromodulation
Background:
- Total hip arthroplasty (THA) effectively treats hip conditions like osteoarthritis, but persistent postoperative pain affects up to 28% of patients.
- Currently, non-pharmacological treatments for persistent pain after THA are limited.
- Posttraumatic arthritis can lead to chronic pain and functional deficits following THA.
Observation:
- A 53-year-old male patient experienced persistent pain and weakness after posttraumatic THA.
- He underwent treatment with a percutaneous peripheral nerve stimulator targeting the femoral nerve.
- Stimulation parameters were adjusted from sensory-level (100 Hz) to motor-level (12 Hz).
Findings:
- The patient demonstrated significant improvement in hip flexion strength, increasing from 10.36 kg to 23.04 kg.
- Functional outcomes improved, with the Lower Extremity Functional Scale score rising from 43.75% to 67.5% within five weeks.
- The treatment successfully alleviated chronic pain and weakness post-THA.
Implications:
- Peripheral nerve stimulation presents a promising non-pharmacological option for managing persistent pain and weakness after THA.
- This approach may be particularly beneficial for patients with posttraumatic arthritis.
- Further research into neuromodulation techniques could enhance recovery and quality of life for THA patients.

