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Assessment of antiprotease activity of some carbamate derivatives
Journal of Pharmaceutical Sciences
|April 1, 1985
Abstract:
Six carbamate derivatives were tested for inhibitory activity towards porcine pancreatic elastase, trypsin, and chymotrypsin. Only three esters that are isatoic anhydride derivatives were found to inhibit elastase competitively but nonspecifically. KI values for the best two inhibitors were determined from Dixon plots.
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