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A Systematic Review Evaluating Cinnamon's Effects on Glucose Utilizing a Ranking System to Assess Bias and Study
Hebat Bakhach1, Monika Nuffer1, Shasta Tall Bull1
1Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA.
Cinnamon may offer modest benefits for blood glucose control in diabetes. Its strong safety profile supports its use alongside traditional diabetes medications.
Area of Science:
- Nutritional Science
- Endocrinology
- Pharmacology
Background:
- Cinnamon is a popular supplement for diabetes management.
- Evidence on its efficacy for glucose control requires strategic evaluation.
Purpose of the Study:
- To systematically evaluate literature on cinnamon's effects on blood glucose.
- To assess various cinnamon species and study quality for reliable conclusions.
Main Methods:
- Systematic literature search following PRISMA guidelines across multiple databases.
- Data extraction and study quality assessment using Risk of Bias 2 and Heyland Methodological Quality Scoring tools.
- Analysis of 45 studies focusing on cinnamon and blood glucose in human subjects.
Main Results:
- Initially, 62% of studies showed statistically significant positive effects on blood glucose control.
- After quality and bias ranking, this figure decreased to approximately 50%.
- Cinnamon demonstrated a favorable safety profile with minimal adverse effects reported.
Conclusions:
- Cinnamon supplementation likely provides a modest benefit for blood glucose management.
- Given its safety, cinnamon can be considered as an adjunctive therapy for diabetes.
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