Survival and clinicopathological significance of B7-H3 in bladder cancer: a systematic review and meta-analysis
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View abstract on PubMed
Summary
This summary is machine-generated.B7-H3 protein is elevated in bladder tumors and linked to infiltration and recurrence. However, this systematic review found no significant association between B7-H3 expression and overall survival in bladder cancer patients.
Area Of Science
- Oncology
- Immunology
- Molecular Biology
Background
- B7-H3 protein's role in cancer prognosis is debated.
- Its significance in bladder cancer remains unclear.
- This study addresses the knowledge gap through meta-analysis.
Conclusions
- B7-H3 is implicated in bladder cancer infiltration and recurrence.
- B7-H3 is not a definitive prognostic biomarker for bladder cancer.
- Further large-scale, diverse studies are needed for validation.
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