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Updated: Jul 1, 2025

Noninvasive, High-throughput Determination of Sleep Duration in Rodents
Published on: April 18, 2018
Sleep duration and lipid metabolism in patients with diabetes mellitus: from the POWER2DM study
Isabel Perez-Corral1,2,3,4, Francisco Gomez-Delgado1,2,3,4, Merel M Ruissen5
1Lipids and Atherosclerosis Unit, Internal Medicine Unit, Reina Sofia University Hospital, Avda. Menendez Pidal, S/N., 14004 Cordoba, Spain.
Abstract:
This study assesses the association between sleep duration and plasma lipid profiles in people with diabetes mellitus (DM). Sleep duration data were obtained in 91 patients from the POWER2DM study (NCT03588104). The patients were divided in tertiles, based on their sleep duration, and blood samples were obtained at the beginning and after 9 months. Significant differences were found, specifically, patients in Tertile 3 (≥ 7.51 h) showed lower plasma levels of high-density lipoprotein cholesterol HDL-c (p < 0.05), apolipoprotein A1 (apo-A1; p < 0.05) and low HDL-c/apo-A1 ratio (p < 0.05). This study shows that sleep duration is associated with plasma lipid profiles in people with DM.
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