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[Long-term course of aortic arch syndrome caused by arteriosclerosis]
Insights
Extracranial cerebrovascular disease presents a poorer prognosis and higher cardiovascular complication rates than the general population. However, surgical intervention and anticoagulant therapy can improve outcomes and survival rates.
Area of Science:
- Vascular Surgery
- Cardiology
- Neurology
Context:
- Extracranially conditioned cerebrovascular disease impacts prognosis and complication rates.
- Patients exhibit earlier onset and more comorbidities compared to general populations.
- Cardiovascular complications include myocardial infarction and apoplexy.
Purpose:
- To analyze the prognosis and treatment outcomes of extracranially conditioned cerebrovascular disease.
- To compare the disease course with peripheral and coronary arteriosclerosis.
- To evaluate the efficacy of surgical reconstruction and anticoagulant therapy.
Summary:
- The disease course is characterized by a worse prognosis (11 years older) and higher cardiovascular complication rates (myocardial infarction, apoplexy).
- Despite complications, the prognosis is more favorable than peripheral and coronary arteriosclerosis.
- Operative vessel reconstruction provides lasting symptom improvement.
- Anticoagulant therapy retards arteriosclerosis progression and improves survival.
Impact:
- Surgical intervention and anticoagulant therapy offer significant benefits for patients.
- Understanding disease characteristics aids in better patient management and risk stratification.
- This research contributes to improved treatment strategies for cerebrovascular disorders.
Abstract:
The course of the extracranially conditioned cerebrovascular disease is characterized by a worse prognosis in comparison with the average population of the GDR (11 years older) and by increased cardiovascular complication rate (every fifth patient suffered a myocardial infarction, every fourth patient suffered an apoplexy). Younger age of manifestation and increasing number of concomitant diseases form the basis of a course which is altogether endangered by complications, which, however, compared with peripheral and coronary arteriosclerosis, is more favourable. Operative reconstruction of the path of a vessel leads to an enduring improvement of the picture of the complaint. The total prognosis corresponds to the so-called spontaneous course. Under permanent treatment with anticoagulants a retardation of the general progressing of arteriosclerosis and improvement of the survival rates is to be proved.