Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bird swarm optimized chaotic lattice framework for parallel multi image encryption.

Scientific reports·2026
Same author

Structural and mechanistic insights into the catalytic versatility of lysyl hydroxylases in collagen post-translational modifications.

The Journal of biological chemistry·2026
Same author

Co-eluting post-translational modification isoforms in collagen reveal fundamental challenge of LC-MS/MS site-specific analysis.

Biochimica et biophysica acta. Proteins and proteomics·2026
Same author

Prolyl-3-hydroxylase 1 is a central regulator of collagen post-translational modifications and the collagen biosynthetic network.

The Journal of biological chemistry·2026
Same author

Deciphering the Intratissue-Specific Collagen PTM Site-Specific Heterogeneity in Human Adrenal Extracellular Matrix.

Biochemistry·2026
Same author

Ligand Design Enables Introduction of Nonaromatic Arylating Agents in Palladium-Catalyzed C-H Arylation of Arenes.

Journal of the American Chemical Society·2026

Related Experiment Video

Updated: Jul 1, 2025

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides
07:03

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides

Published on: January 31, 2014

12.0K

ColPTMScape: An open access knowledge base for tissue-specific collagen PTM maps.

Ashutosh Joshi1, Ayush Nigam1, Lalit Narayan Mudgal1

  • 1School of Biosciences and Bioengineering, Indian Institute of Technology (IIT) Mandi, Himachal Pradesh 175075, India.

Matrix Biology Plus
|March 12, 2024
PubMed
Summary

Scientists created ColPTMScape, a knowledge base for collagen post-translational modifications (PTMs). This resource consolidates data on collagen PTMs, aiding research into extracellular matrix remodeling and disease.

Keywords:
CollagenCollagen PTMsExtracellular matrixKnowledge basePTM identificationPTM quantitation

More Related Videos

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools
07:58

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

Published on: November 11, 2020

6.1K
Revealing the Cytoskeletal Organization of Invasive Cancer Cells in 3D
11:09

Revealing the Cytoskeletal Organization of Invasive Cancer Cells in 3D

Published on: October 26, 2013

15.8K

Related Experiment Videos

Last Updated: Jul 1, 2025

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides
07:03

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides

Published on: January 31, 2014

12.0K
Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools
07:58

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

Published on: November 11, 2020

6.1K
Revealing the Cytoskeletal Organization of Invasive Cancer Cells in 3D
11:09

Revealing the Cytoskeletal Organization of Invasive Cancer Cells in 3D

Published on: October 26, 2013

15.8K

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Bioinformatics

Background:

  • Collagen is a critical component of the extracellular matrix (ECM).
  • Collagen post-translational modifications (PTMs) are vital during ECM remodeling.
  • Variations in collagen PTMs are implicated in pathological conditions.

Purpose of the Study:

  • To develop a centralized, accessible knowledge base for collagen PTMs.
  • To consolidate diverse data on site-specific collagen PTMs.
  • To facilitate research on ECM remodeling and related diseases.

Main Methods:

  • Data compilation from scientific literature.
  • Development of a web-based knowledge base (ColPTMScape).
  • Database curation of identified, quantified, and mapped collagen PTM sites.

Main Results:

  • ColPTMScape provides a comprehensive repository of collagen PTM information.
  • The database includes site-specific PTMs, quantified PTM sites, and PTM maps.
  • Users can explore variations in collagen PTMs across different tissues and organisms.

Conclusions:

  • ColPTMScape serves as a valuable resource for the scientific community, particularly matrix biologists.
  • The knowledge base enhances understanding of collagen PTMs in ECM remodeling.
  • Facilitates research into the role of collagen PTMs in health and disease.