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Published on: April 8, 2013
Research Progress and Clinical Value of Subendocardial Viability Ratio
Haotai Xie1, Lan Gao1,2, Fangfang Fan1,2
1Department of Cardiology Peking University First Hospital Beijing China.
Insights
The subendocardial viability ratio assesses heart oxygen supply and demand, aiding in the evaluation of coronary microcirculation and predicting cardiovascular events. This vital index offers insights into various heart conditions.
Area of Science:
- Cardiology
- Physiology
Background:
- Cardiovascular disease is a leading global cause of death.
- Ischemic heart disease, driven by plaque or microvascular dysfunction, impairs myocardial perfusion.
- Acute myocardial infarction can result from severe coronary blood flow obstruction.
Purpose of the Study:
- To review the applications and clinical significance of the subendocardial viability ratio.
- To highlight recent research progress concerning this myocardial perfusion index.
- To underscore its predictive value for cardiovascular events and mortality.
Main Methods:
- Review of existing literature on the subendocardial viability ratio.
- Analysis of its role in evaluating myocardial perfusion and coronary microcirculation.
- Examination of its association with arterial stiffness and clinical outcomes.
Main Results:
- The subendocardial viability ratio effectively balances myocardial oxygen supply and demand.
- It is a valuable tool for assessing coronary microcirculation function.
- The ratio shows predictive potential for adverse cardiovascular events and mortality across diverse populations.
Conclusions:
- The subendocardial viability ratio is crucial for evaluating myocardial perfusion.
- Its clinical significance extends to various conditions like hypertension, diabetes, and CKD.
- Further research and application of this ratio can improve cardiovascular disease management.
Abstract:
Cardiovascular disease remains the leading cause of morbidity and mortality worldwide, with ischemic heart disease being a major contributor, either through coronary atherosclerotic plaque-related major vascular disease or coronary microvascular dysfunction. Obstruction of coronary blood flow impairs myocardial perfusion, which may lead to acute myocardial infarction in severe cases. The subendocardial viability ratio, also known as the Buckberg index, is a valuable tool for evaluation of myocardial perfusion because it reflects the balance between myocardial oxygen supply and oxygen demand. The subendocardial viability ratio can effectively evaluate the function of the coronary microcirculation and is associated with arterial stiffness. This ratio also has potential value in predicting adverse cardiovascular events and mortality in various populations. Moreover, the subendocardial viability ratio has demonstrated clinical significance in a range of diseases, including hypertension, aortic stenosis, peripheral arterial disease, chronic kidney disease, diabetes, and rheumatoid arthritis. This review summarizes the applications of the subendocardial viability ratio, its particular progress in the relevant research, and its clinical significance in cardiovascular diseases.
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