Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Years of life lost in patients with a false-negative diagnosis of primary melanoma. A prospective study of the German Central Malignant Melanoma Registry involving 9063 patients over 28 years.

Nature communications·2026

Same author

In Vivo Microscopic Features of Acne vulgaris Revealed via LC-OCT.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2026

Same author

Low-Dose Tamoxifen in Noninvasive Breast Neoplasia: Long-Term Results From an Individual-Participant Data Pooled Analysis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026

Same author

LC-OCT in differentiating lichen planus from discoid lupus erythematosus in challenging lesions.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026

Same author

Line-Field Confocal Optical Coherence Tomography (LC-OCT) of Pilomatricoma.

Pediatric dermatology·2026

Same author

Serial cycle threshold to assess the infectious potential of SARS-CoV-2: A systematic review.

Epidemiology and infection·2026

Search research articles

Related Experiment Video

Updated: Jul 1, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

Risk Factors and Innovations in Risk Assessment for Melanoma, Basal Cell Carcinoma, and Squamous Cell Carcinoma.

K Wunderlich¹, M Suppa^1,2, S Gandini³

¹Department of Dermatology, Hôpital Erasme, Université Libre de Bruxelles, 1070 Brussels, Belgium.

|March 13, 2024

Summary

Skin cancer is a common, preventable disease. Understanding diverse risk factors like UV exposure and genetics helps identify high-risk individuals for early diagnosis and targeted prevention strategies.

Keywords:

basal cell carcinoma melanoma risk scores skin cancer risk factors squamous cell carcinoma

More Related Videos

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

Related Experiment Videos

Last Updated: Jul 1, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

Area of Science:

Oncology
Dermatology
Public Health

Background:

Skin cancer is the most common cancer worldwide and is largely preventable.
Risk factors include extrinsic (UV exposure, behavior) and intrinsic (genetics) elements.
Different skin cancer types (melanoma, basal cell carcinoma, squamous cell carcinoma) have distinct risk profiles.

Purpose of the Study:

To elucidate the varied risk factors contributing to different skin cancer types.
To emphasize the importance of precise risk factor knowledge for early diagnosis and treatment.
To highlight the development of risk scores for identifying high-risk populations.

Main Methods:

Review of existing literature on skin cancer risk factors.
Analysis of extrinsic factors (UV exposure, behavioral patterns).
Analysis of intrinsic factors (genetic predispositions).

Main Results:

Identified specific extrinsic and intrinsic risk factors for melanoma, basal cell carcinoma, and squamous cell carcinoma.
Demonstrated that risk factors vary significantly across different skin cancer subtypes.
Confirmed the utility of risk scores in pinpointing individuals at elevated risk.

Conclusions:

Precise understanding of individual risk factors is crucial for effective skin cancer prevention and management.
Risk stratification through scores aids in targeted interventions for high-risk individuals.
Advances in risk factor knowledge contribute to improved public health strategies for mitigating skin cancer burden.