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Updated: Jul 1, 2025

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
Association between Preconception Dietary Fiber Intake and Preterm Birth: The Japan Environment and Children's Study
Takahiro Omoto1,2, Hyo Kyozuka1,2, Tsuyoshi Murata1,2
1Fukushima Regional Center for the Japan Environmental and Children's Study, Fukushima 960-1295, Japan.
Insights
Higher preconception dietary fiber intake is linked to a lower risk of early preterm birth (before 34 weeks). This suggests dietary fiber may play a role in preventing premature births.
Area of Science:
- Obstetrics and Gynecology
- Nutritional Science
- Public Health
Background:
- Preterm birth (PTB) significantly contributes to infant mortality and morbidity.
- Understanding modifiable risk factors like diet is crucial for PTB prevention.
Purpose of the Study:
- To investigate the association between preconception dietary fiber intake and the incidence of preterm birth.
- To analyze if higher fiber consumption before pregnancy impacts PTB risk.
Main Methods:
- Prospective cohort study using data from 85,116 pregnancies in the Japan Environmental and Children's Study (JECS).
- Participants were grouped into quintiles based on preconception dietary fiber intake.
- Multiple logistic regression analysis was employed to assess the association with PTB.
Main Results:
- Higher dietary fiber intake (Q3-Q5) was associated with a reduced risk of PTB before 34 weeks compared to the lowest intake group (Q1).
- Specifically, Q3, Q4, and Q5 showed significantly lower adjusted odds ratios for PTB before 34 weeks.
- No significant association was found between preconception dietary fiber intake and PTB before 37 weeks.
Conclusions:
- Increased preconception dietary fiber intake is correlated with a decreased risk of preterm birth before 34 weeks gestation.
- Dietary fiber may be a beneficial factor in preventing early preterm birth.
- Consideration of dietary fiber recommendations in preconception care is warranted.
Abstract:
Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality. Therefore, this study aimed to determine whether preconception dietary fiber intake is associated with PTB. This was a prospective cohort Japan Environmental and Children's Study (JECS). The study population comprised 85,116 singleton live-birth pregnancies from the JECS database delivered between 2011 and 2014. The participants were categorized into five groups based on their preconception dietary fiber intake quintiles (Q1 and Q5 were the lowest and highest groups, respectively). Multiple logistic regression analysis was performed to determine the association between preconception dietary fiber intake and PTB. Multiple logistic regression analysis revealed that the risk for PTB before 34 weeks was lower in the Q3, Q4, and Q5 groups than in the Q1 group (Q3: adjusted odds ratio [aOR] 0.78, 95% confidence interval [CI] 0.62-0.997; Q4: aOR 0.74, 95% CI 0.57-0.95; Q5: aOR 0.68, 95% CI 0.50-0.92). However, there was no significant difference between preconception dietary fiber intake and PTB before 37 weeks. In conclusion, higher preconception dietary fiber intake correlated with a reduced the risk for PTB before 34 weeks. Therefore, new recommendations on dietary fiber intake as part of preconception care should be considered.
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