Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 1, 2025

Stereolithographic 3D Printing with Renewable Acrylates
08:28

Stereolithographic 3D Printing with Renewable Acrylates

Published on: September 12, 2018

9.5K

Additive and Lithographic Manufacturing of Biomedical Scaffold Structures Using a Versatile Thiol-Ene Photocurable

Michael Kainz1, Stjepan Perak1, Gerald Stubauer1

  • 1Functional Surfaces and Nanostructures, Profactor GmbH, 4407 Steyr-Gleink, Austria.

Polymers
|March 13, 2024
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhancing bioactivity of 3D-printed porous scaffolds with self-assembling peptide hydrogels for cartilage tissue engineering.

3D printing in medicine·2026
Same author

The Influence of Micropatterned Surfaces on Platelet Adhesion to Reduce the Risk of Thrombus Formation in Left Ventricular Assist Devices.

Annals of biomedical engineering·2026
Same author

Fabrication and characterisation of Ti and DLC coatings on metamaterial-architecture-inspired 3D-printed polymer substrates.

The International journal, advanced manufacturing technology·2026
Same author

Femtosecond Laser Engraving Promotes the Repopulation of Decellularized Human Articular Cartilage.

Journal of tissue engineering and regenerative medicine·2026
Same author

Development and external validation of a mixed-reality aneurysm clipping simulator.

Neurosurgical review·2025
Same author

Rupture risk assessment for AComA aneurysms with morphological, hemodynamic and structural mechanical analysis.

PloS one·2025
This summary is machine-generated.

This study introduces a versatile thiol-ene resin for advanced 3D bioprinting and lithography. The material enables rapid, oxygen-tolerant fabrication of multiscale biomimetic scaffolds and biointerfaces.

Area of Science:

  • Materials Science
  • Biotechnology
  • Additive Manufacturing

Background:

  • Photopolymerization techniques are crucial for fabricating multiscale structures for biomimetic scaffolds and biointerfaces.
  • Existing resins are often specific to a single fabrication technology, limiting their versatile application.
  • There is a need for adaptable resins suitable for various additive and lithographic manufacturing processes.

Purpose of the Study:

  • To develop and characterize a versatile photopolymerizable resin for additive and lithographic manufacturing.
  • To demonstrate the resin's suitability for biofabrication applications requiring fast curing kinetics in the presence of oxygen.
  • To enable the fabrication of multiscale scaffolds and biointerfaces with controlled architectures.

Main Methods:

Keywords:
additive manufacturingbiomimetic scaffoldphotopolymerisationthiol-ene

More Related Videos

Novel Process for 3D Printing Decellularized Matrices
08:14

Novel Process for 3D Printing Decellularized Matrices

Published on: January 7, 2019

7.1K
Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
07:05

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

Published on: September 22, 2015

10.1K

Related Experiment Videos

Last Updated: Jul 1, 2025

Stereolithographic 3D Printing with Renewable Acrylates
08:28

Stereolithographic 3D Printing with Renewable Acrylates

Published on: September 12, 2018

9.5K
Novel Process for 3D Printing Decellularized Matrices
08:14

Novel Process for 3D Printing Decellularized Matrices

Published on: January 7, 2019

7.1K
Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
07:05

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

Published on: September 22, 2015

10.1K
  • Utilized a resin based on thiol-ene chemistry, known for low oxygen inhibition, minimal shrinkage, and high monomer conversion.
  • Applied the resin in 3D inkjet printing, digital light processing, and nanoimprint lithography.
  • Fabricated scaffolds and patterned surfaces across a size range from 150 nm to 10 mm.

Main Results:

  • The thiol-ene resin demonstrated fast curing kinetics, even in the presence of oxygen.
  • Successfully fabricated diverse structures including bioinspired porous scaffolds, patterned plates, and micro/submicro surfaces.
  • Achieved fabrication across six orders of magnitude in height (150 nm to 10 mm).

Conclusions:

  • The developed thiol-ene resin offers a versatile platform for additive and lithographic biofabrication.
  • Its properties, including noncytotoxicity, degradability, and component availability, make it ideal for prototyping tissue engineering scaffolds.
  • The resin supports rapid, oxygen-tolerant fabrication for creating complex multiscale biomaterials.