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Related Concept Videos

Muscles of the Eye01:20

Muscles of the Eye

The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and rotating...
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
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Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

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Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
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Eyelash serums: A comprehensive review.

Maya Baiyasi1, Kayla St Claire2, Meredith Hengy1

  • 1Wayne State University School of Medicine, Detroit, Michigan, USA.

Journal of Cosmetic Dermatology
|March 13, 2024
PubMed
Summary
This summary is machine-generated.

Eyelash serums, containing prostaglandin analogs like bimatoprost, can enhance eyelash appearance. However, regulatory oversight is limited, necessitating informed dermatologists to guide patients on safe, effective use of these popular cosmeceuticals.

Keywords:
eyelash growtheyelash serumhair growthserum

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Area of Science:

  • Cosmeceuticals and Dermatology
  • Ophthalmology
  • Clinical Pharmacology

Background:

  • Eyelash serums, including prescription and over-the-counter (OTC) options, are increasingly popular for improving eyelash appearance.
  • These products utilize biologically active molecules, primarily prostaglandin analogs and non-prostaglandin analogs, claiming enhanced eyelash strength, length, luster, and thickness.
  • The lack of mandatory FDA efficacy and safety assessments for OTC eyelash enhancements poses potential health risks.

Purpose of the Study:

  • To explore the proposed benefits and adverse effects of eyelash serums.
  • To provide evidence-based clinical recommendations for the use of eyelash serums.
  • To enhance understanding of eyelash serum safety considerations.

Main Methods:

  • A comprehensive electronic literature search was conducted across PubMed, Embase, Cochrane Central, and Google Scholar.
  • Articles were independently evaluated by two researchers for relevance, focusing on eyelash serum ingredients.
  • Clinical recommendations were formulated based on the Oxford Centre for Evidence-Based Medicine criteria.

Main Results:

  • Bimatoprost demonstrates efficacy in eyelash enhancement, with substantial safety and adverse effect data.
  • Other prostaglandin ingredients show potential benefits, but further research is needed to fully elucidate their safety profiles.
  • Non-prostaglandin ingredients show promise, yet require more studies due to limited formal evidence in eyelash serum applications.

Conclusions:

  • The cosmeceutical market for eyelash serums is expanding rapidly.
  • Dermatologists must possess current, evidence-based knowledge of both prescription and OTC eyelash serum products.
  • Informed recommendations are crucial for guiding patients on the safe and effective use of eyelash serums.