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Correction: Sun et al. Engineered Adipose-Derived Stem Cells Overexpressing RXFP1 via CRISPR Activation Ameliorate Erectile Dysfunction in Diabetic Rats. <i>Antioxidants</i> 2023, <i>12</i>, 171.

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Bibliometric and Visualization Analysis of Stem Cell Therapy for Erectile Dysfunction.

Taotao Sun1, Yipiao Liu2, Penghui Yuan1

  • 1Department of Urology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.

Drug Design, Development and Therapy
|March 13, 2024
PubMed
Summary

Stem cell therapy (SCT) shows great potential for treating erectile dysfunction (ED). This bibliometric analysis reveals increasing research, with China and the USA leading, and highlights future focuses on exosomes and clinical translation.

Keywords:
VOSviewerbibliometric analysiscitespaceerectile dysfunctionstem cellsvisualization

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Area of Science:

  • Regenerative Medicine
  • Urology
  • Andrology

Background:

  • Erectile dysfunction (ED) is a prevalent male condition impacting health.
  • Stem cell therapy (SCT) is emerging as a promising treatment for ED.
  • Understanding research trends in SCT for ED is crucial for advancing the field.

Purpose of the Study:

  • To conduct a comprehensive bibliometric analysis of research on stem cell therapy for erectile dysfunction.
  • To identify development trends and research frontiers in SCT for ED.

Main Methods:

  • Bibliometric and visualization analysis of publications from the Web of Science Core Collection.
  • Utilized CiteSpace and VOSviewer software for data analysis.

Main Results:

  • 524 publications were analyzed, showing a year-on-year increase.
  • China and the USA are the most productive countries; University of California San Francisco is a leading institution.
  • Mesenchymal stem cells (from adipose and bone marrow) are most common; future research focuses on exosomes, tissue engineering, and clinical translation.

Conclusions:

  • Research in SCT for ED is gaining global attention.
  • This study provides insights into the research landscape and frontiers.
  • Further preclinical and clinical studies are needed to explore mechanisms and promote translation.