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Updated: May 12, 2026

Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow
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Sequential carotid Doppler study in acute stroke and its clinical correlation: A prospective study

Ashutosh Kumar Karn1, Shamrendra Narayan2, Abdul Qavi1

  • 1Department of Neurology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Journal of Neurosciences in Rural Practice
|March 13, 2024
PubMed

Insights

Resistive index (RI) and pulsatility index (PI) from carotid Doppler can predict stroke outcomes. Increased PI in patients with unfavorable outcomes suggests autoregulation failure, indicating a poor prognosis.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Medical Imaging

Background:

  • Cerebrovascular hemodynamics are crucial in stroke assessment.
  • Resistive index (RI) and pulsatility index (PI) via carotid Doppler reflect cranial vasculature status.
  • These indices correlate with stroke severity and patient outcomes.

Purpose of the Study:

  • To compare hospital stay and stroke severity using RI and PI of internal carotid arteries.
  • To investigate the association between carotid Doppler parameters and stroke outcomes.
  • To evaluate the predictive value of RI and PI in acute stroke patients.

Main Methods:

  • Included 101 patients (>18 years) within 48 hours of anterior circulation stroke.
  • Divided patients into favorable and unfavorable outcome groups based on length of stay (LOS).
  • Assessed patients clinically and performed carotid Doppler studies on days 1, 3, and 5, correlating parameters with LOS and stroke severity.

Main Results:

  • A significant decrease in RI and PI was observed from days 1-3 in the favorable outcome group.
  • Patients with unfavorable outcomes showed a significant PI increase from days 1-3 and 1-5.
  • The National Institutes of Health Stroke Scale score significantly decreased in the favorable group from days 1-5.

Conclusions:

  • Elevated PI in unfavorable outcome, prolonged LOS patients suggests impaired cerebral autoregulation.
  • Carotid Doppler offers a simple bedside method for predicting acute stroke outcomes.
  • RI and PI are valuable non-invasive tools for assessing stroke severity and prognosis.
Abstract

Keywords:
Carotid DopplerLength of stayNational Institutes of Health Stroke ScalePulsatility indexResistive indexStroke

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