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Updated: Jul 1, 2025

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Proparacaine Overuse in Corneal Abrasions at the Emergency Department: A Case Series
Avery Zhou1, Anja Rabljenovic, Thomas L Steinemann
1Kirk Kerkorian School of Medicine (A.Z.), Las Vegas, NV; University of Toledo College of Medicine and Life Sciences (A.R.), Toledo, OH; Case Western Reserve University School of Medicine (T.L.S.), Cleveland, OH; and MetroHealth Medical Center Division of Ophthalmology (T.L.S.), Cleveland, OH.
Abstract:
Corneal abrasions are among the most common ophthalmic injuries in the emergency department (ED) and primarily present as severe ocular pain. Topical anesthetics provide temporary analgesia, but overuse is associated with complications including further corneal injury, infection, and vision loss. This case series describes three patients who used a 15-mL bottle of 0.05% proparacaine hydrochloride ophthalmic solution after discharge from the ED and returned within three days with corneal injury and pain. Although the use of topical anesthetics is traditionally discouraged by ophthalmologists, publications in the emergency medicine literature support their use. We review the literature surrounding topical anesthetic use in the ED setting and caution against prescribing patients topical anesthetics for corneal abrasions, particularly without patient counseling and significant restriction of anesthetic supply.
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