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Harnessing regulatory T cells to establish immune tolerance

Patrick Ho1, Ellen Cahir-McFarland2, Jason D Fontenot3

  • 1Diabetes Center, University of California San Francisco, San Francisco, CA 94143, USA.

Science Translational Medicine
|March 13, 2024
PubMed

Engineered regulatory T (Treg) cells have emerged as precision therapeutics aimed at inducing immune tolerance while reducing the risks associated with generalized immunosuppression. This Viewpoint highlights the opportunities and challenges for engineered Treg cell therapies in treating autoimmune and other inflammatory diseases.

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