Related Experiment Video
Updated: Jul 1, 2025
08:32
Orthotopic Aortic Transplantation: A Rat Model to Study the Development of Chronic Vasculopathy
Published on: December 4, 2010
12.2K
Livedoid vasculopathy
Melissa C Leeolou, Kerri E Rieger, Jennifer E Yeh1
1Department of Dermatology, Stanford University School of Medicine, California, USA. jeyeh@stanford.edu.
Dermatology Online Journal
|March 13, 2024
Summary
Livedoid vasculopathy is a rare, painful vascular disorder causing skin ulcers due to blood clots. Case reports are crucial for understanding its presentation and treatment options.
Area of Science:
- Vascular Medicine
- Dermatology
- Pathology
Background:
- Livedoid vasculopathy is a rare, painful thrombo-occlusive vascular disorder.
- It is characterized by spontaneous thrombosis in medium-size arterioles.
- This condition leads to localized hypoxia and skin ulceration.
Purpose of the Study:
- To expand collective knowledge on livedoid vasculopathy.
- To document the presentation of livedoid vasculopathy.
- To report on the response to various therapies for livedoid vasculopathy.
Main Methods:
- Case reports are the primary method used.
- Detailed clinical presentation is documented.
- Therapeutic interventions and outcomes are recorded.
Main Results:
- Case reports provide insights into this rare condition.
- Understanding of livedoid vasculopathy's varied presentations is enhanced.
- Effectiveness of different treatments is highlighted through case studies.
Conclusions:
- Case reports are essential for advancing the understanding of rare diseases like livedoid vasculopathy.
- Further case reports are needed to fully elucidate optimal therapeutic strategies.
- This approach aids in managing the painful symptoms and complications of livedoid vasculopathy.
Related Concept Videos
01:16Vascular Spasm
1.4K
The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
1.4K
01:15Veins of Lower Limbs
809
The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the...
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the...
809
01:10Veins as Blood Reservoirs
4.5K
Veins, while chiefly responsible for circulating blood back to the heart, also function as storage vessels for blood. They house approximately 64 percent of the body's total blood volume, a feat made possible by their high capacitance—the inherent ability to expand and accommodate large volumes of blood, even under low pressure. The large diameter and thin walls of veins augment their distensibility, significantly more so than arteries, due to their classification as capacitance...
4.5K
01:17Veins of Upper Limbs
867
The human circulatory system, a marvel of biological engineering, is a complex network of vessels that transport blood throughout the body. Among these, the veins responsible for carrying blood from the upper limbs are divided into two categories: deep and superficial.
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
867
01:08Venules
835
Venules are an integral part of the microscopic circulatory system that bridges the gap between capillaries and veins.
Venules are much smaller in diameter compared to their larger counterparts, the veins. They are generally 8 to 100 micrometers in diameter, significantly smaller than the size of veins. The walls of venules are thin, consisting of the endothelium, a thin layer of connective tissue, and occasionally a few smooth muscle cells. This structural simplicity is a stark contrast...
Venules are much smaller in diameter compared to their larger counterparts, the veins. They are generally 8 to 100 micrometers in diameter, significantly smaller than the size of veins. The walls of venules are thin, consisting of the endothelium, a thin layer of connective tissue, and occasionally a few smooth muscle cells. This structural simplicity is a stark contrast...
835
01:07Development of Blood Vessels
582
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
582