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Cutaneous erythematous lupus with acneiform presentation.

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Cutaneous lupus erythematosus (CLE) can mimic acne, leading to underdiagnosis. Early histopathologic diagnosis is crucial for recognizing CLE

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Area of Science:

  • Dermatology
  • Immunology

Background:

  • Cutaneous lupus erythematosus (CLE) presents with diverse clinical manifestations.
  • Acneiform presentations of CLE are often misdiagnosed as inflammatory acne.

Observation:

  • A 57-year-old woman presented with a nine-month history of facial blemishes, nodules, and swelling, initially treated as acne.
  • Examination revealed malar nodules, comedones, pustules, atrophic scars, and hyperpigmentation.
  • Ear itching was also noted.

Findings:

  • Histopathology showed atrophic epidermis, hyperkeratosis, vacuolar degeneration, lymphohistiocytic infiltrate, and mucin deposits.
  • These findings confirmed CLE despite the acneiform appearance.

Implications:

  • This case highlights the importance of considering CLE in acneiform eruptions.
  • Histopathological examination is essential for accurate diagnosis of CLE.
  • Recognizing the varied presentations of CLE is key for timely and appropriate patient management.