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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Pre-emptive Aortic Side Branch Embolization during Endovascular Aneurysm Repair Using the Excluder Stent-Graft
Koji Sasaki1, Masato Yamaguchi1, Tomoyuki Gentsu1
1Department of Diagnostic and Interventional Radiology, Kobe University Hospital, Kobe, Hyogo, Japan.
Pre-emptive transcatheter arterial embolization (P-TAE) for aortic side branches before EVAR is safe and effective. This strategy helps reduce Type 2 endoleaks and promotes early aneurysm sac shrinkage.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Endovascular Repair
Background:
- Type 2 endoleaks (EL2) are a common complication after endovascular aneurysm repair (EVAR).
- Aortic side branches (ASBs) are a frequent source of EL2, potentially leading to aneurysm sac enlargement and reintervention.
- Pre-emptive strategies are needed to mitigate EL2 risk before EVAR.
Purpose of the Study:
- To evaluate the safety and effectiveness of pre-emptive transcatheter arterial embolization (P-TAE) for ASBs.
- To prevent Type 2 endoleaks (EL2) in patients undergoing EVAR with the Excluder stent-graft system.
- To assess the impact of P-TAE on aneurysmal sac dynamics and reintervention rates.
Main Methods:
- Prospective, multicenter study involving 80 patients undergoing EVAR with the Excluder stent-graft.
- Pre-emptive embolization of patent ASBs was performed prior to EVAR.
- Contrast-enhanced CT scans were used for follow-up at 1 and 6 months post-EVAR to assess EL2 incidence and sac diameter changes.
Main Results:
- P-TAE was successfully performed in all patients with a high rate of coil embolization (81.6%) of ASBs.
- The incidence of EL2 at 6 months was 25.7% (18 of 70 patients).
- Aneurysmal sac shrinkage (≥5 mm) was observed in 30.0% at 6 months and 40.9% at 12 months, with only one reintervention for EL2 within one year.
Conclusions:
- Pre-emptive transcatheter arterial embolization (P-TAE) for aortic side branches is a safe and effective adjunct to EVAR.
- P-TAE contributes to early aneurysmal sac shrinkage.
- This approach reduces the need for reintervention due to Type 2 endoleaks within one year post-EVAR.
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