Diagnostic advances in interstitial lung disease

In summary, the interstitial lung diseases represent a large group of diseases with similar clinical and pathophysiologic features but widely different etiologies. A definitive diagnosis usually depends on obtaining tissue; however, a clinical diagnosis may be adequate for therapeutic intervention in selected cases. A schematic approach to the evaluation of interstitial lung disease is presented in Figure 5. Currently, there is intense research in developing accurate noninvasive tests not only to enhance diagnosis but also to help monitor and modulate treatment.