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Metaplastic Breast Cancer with Squamous Differentiation: Beyond the Recognized Statistics.
Rania Zaki Fallatah1, Dhuha N Boumarah2, Ghadeer Hajjaj2
1College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Medical Archives (Sarajevo, Bosnia and Herzegovina)
|March 14, 2024
Summary
Metaplastic breast cancer, a rare carcinoma, often presents as a rapidly growing mass. Early detection and prompt management are crucial due to its poor prognosis.
Area of Science:
- Oncology
- Pathology
- Medical Case Reports
Background:
- Metaplastic breast cancer (MBC) is a rare subtype of breast carcinoma, comprising less than 1% of all breast neoplasms.
- It was recognized as an independent pathological diagnosis late in the 20th century.
- MBC often presents in advanced stages with a rapidly growing mass and carries a poor prognosis.
Conclusions:
- Metaplastic breast cancer is a rare and aggressive entity requiring a high index of suspicion for early diagnosis.
- The clinical presentation can mimic other breast cancers, but a tendency for later-stage presentation and poor prognosis necessitates prompt recognition.
- Appropriate management strategies, including neoadjuvant chemotherapy and surgical intervention, are guided by tumor response.
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