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Updated: Jul 1, 2025

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
Published on: January 29, 2019
Combining theranostic/particle therapy with immunotherapy for the treatment of GU malignancies
Karin A Skalina1, Beata Małachowska1, Kunal K Sindhu2
1Department of Radiation Oncology Montefiore Medical Center/Albert Einstein College of Medicine Bronx New York USA.
Abstract:
Particle therapy and radiopharmaceuticals are emerging fields in the treatment of genitourinary cancers. With these novel techniques and the ever-growing immunotherapy options, the combinations of these therapies have the potential to improve current cancer cure rates. However, the most effective sequence and combination of these therapies is unknown and is a question that is actively being explored in multiple ongoing clinical trials. Here, we review the immunological effects of particle therapy and the available radiopharmaceuticals and discuss how best to combine these therapies.
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